Molecular Imaging: Radiopharmaceuticals for PET and SPECT

Molecular Imaging: Radiopharmaceuticals for PET and SPECT
ISBN-10
3540767355
ISBN-13
9783540767350
Series
Molecular Imaging
Category
Medical
Pages
372
Language
English
Published
2009-07-13
Publisher
Springer Science & Business Media
Author
Shankar Vallabhajosula

Description

Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.

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