Drug Design: Methodology, Concepts, and Mode-of-Action

Drug Design: Methodology, Concepts, and Mode-of-Action
ISBN-10
3642179061
ISBN-13
9783642179068
Series
Drug Design
Category
Medical
Language
English
Published
2013-07-10
Publisher
Springer
Author
Gerhard Klebe

Description

Unique work on structure-based drug design, covering multiple aspects of drug discovery and development. Fully colored, many images, computer animations of 3D structures (these only in electronic form). Makes the spatial aspects of interacting molecules clear to the reader, covers multiple applications and methods in drug design. Structures by mode of action, no therapeutic areas. Of high relevance for academia and industrial research. Focus on gene technology in drug design, omics-technologies computational methods experimental techniques of structure determination multiple examples on mode of action of current drugs, ADME-tox properties in drug development, QSAR methods, combinatorial chemistry, biologicals, ribosome, targeting protein-protein interfaces.

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