The endocrine system provides an electrochemical connection from the hypothalamus of the brain to all the organs that control the body metabolism, growth & development, and reproduction. It is important for the survival of all living things. Without a mechanism for reproduction, life would come to an end. Human reproduction is a form of sexual reproduction resulting in the conception of a child, typically involving sexual intercourse between man and woman. During intercourse, the interaction between the male and female reproductive systems results in fertilization of the woman's ovum by the man's sperm, which after a gestation period is followed by childbirth. Many teachers are afraid of discussing reproduction and endocrinology, but if presented as a factual lesson it is easy for the students to understand the principles without the standard giggles.Our goal for writing these lecture notes is to help future biologists to gain a basic understanding of reproduction and endocrinology so that they can handle the subject as per their need. However, these lecture notes are written in a very simple and lucid form and it may also a comprehensive guide.