Anticoagulation Therapy
- ISBN-10
- 9535126660
- ISBN-13
- 9789535126669
- Series
- Anticoagulation Therapy
- Category
- Medical
- Pages
- 152
- Language
- English
- Published
- 2016-09-08
- Publisher
- BoD – Books on Demand
- Authors
- Ozcan Basaran, Murat Biteker
Description
The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there is a substantial number of patients who are on oral anticoagulant therapy. Prothrombin complex concentrate and other plasma concentrates are useful to deal with over-coagulated situations. The efficacy and safety of non-vitamin K antagonist oral anticoagulants have been proven in large phase III trials. The real-world data suggest even better outcomes with these agents compared to vitamin K antagonists.
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