This book illustrates the basics and underlying molecular machinery of cancer cells and biochemical assays that detect the type and stage of cancer through cell signaling biomarkers. It starts with a brief introduction to cancer biomarkers and addresses technologies for identifying and validating cancer biomarkers, biomarkers for cancer drug development, prognostic and diagnostic biomarkers, and microbiome as cancer biomarkers. It reviews predictive biomarkers for anticancer drugs, biomarkers in cancer survival and drug resistance, biomarkers in tumor recurrence and metastasis, the role of the biomarker in immunotherapy and personalized medicine, and the development of a novel cancer biomarker. Finally, this book also underpins the role of nanotechnology in the use and detection of cancer biomarkers for enhanced sensitivity and specificity. Lastly, it discusses the challenges with biomarkers in cancer drug discovery and development. This volume is an indispensable tool for researchers working in the field of cancer and also for clinical oncologists.
Collen , Morris F. , Leonard Rubin , and Lou S. Davis . " Computers in Multiphasic Screening . " In Computers in Biomedical Research , vol . 1 , ed . Ralph W. Stacy and Bruce Waxman , chap . 14. New York : Academic Press , 1965 .
Talwar S, Squire IB, Downie PF, Davies JE, Ng LL. Plasma N terminal pro-brain natriuretic peptide and cardiotrophin 1 are raised in unstable angina. Heart. 2000;84:421-4. Wiese S, Breyer T, Dragu A, Wakili R, Burkard T, Schmidt-Schweda ...
The monoamine oxidase A (MAOA) genetic predisposition to impulsive violence: Is it relevant to criminal trials? ... S., Bloom, L. R., Fathima, S., Feigl, A. B., Gaziano, T., Mowafi, M., Pandya, A., Prettner, K., Rosenberg, L., Seligman, ...
Shepherd, B.S., Burch, A, Ron, B., Richman, N.H., Shimoda, S.K., Stetson, M.H., Lim, C, and Grau, E.G., 1997a, Effects of salinity, dietary levels of protein and 17a- methyltestosterone on growth hormone (GH) and prolactin (tPRL177 and ...
Rising interest in how diseases evolve through the monitoring of biological markers has created the need for enhanced sensing techniques. Immunoassay and matrix-assisted laser desorption/ionization time of flight mass spectrometry...
Bengtson. University of Rhode Island, Department of Biological Sciences, Kingston, RI 02881; Symposium Chairperson and Editor. Biomarkers Brent D. Palmer1 and Kyle W. Selcer2 VITELLOGENIN AS OVERVIEW xiii.
Cardiac Biomarkers in Clinical Practice
This book provides a comprehensive overview of the diagnosis and management of Non-alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatis (NASH).
Opening with an introduction to the field of computational toxicology and its current and potential applications, the volume continues with ’best practices’ in mathematical and computational modeling, followed by chemoinformatics and ...
Biological Indicators of Stress in Fish