Theory and Evaluation of Single-molecule Signals

Theory and Evaluation of Single-molecule Signals
ISBN-10
9812793488
ISBN-13
9789812793485
Category
Science
Pages
416
Language
English
Published
2008
Publisher
World Scientific
Author
Eli Barkai

Description

This book reviews recently developed theoretical and numerical approaches to deal with optical and mechanical signals from individual molecules. The character of data generated by single molecules, and more generally by single nano-objects, qualitatively differs from those obtained in conventional experiments on large ensembles of molecules. Fluctuations, randomness and irreproducibility are central to single-molecule measurements, and the specific methods required to extract reliable and statistically relevant information from them are presented here. With contributions mainly from participants of the ?Theory, Modeling and Evaluation of Single-Molecule Measurements? workshop held in Leiden, the Netherlands, on April 16-20, 2007, this book is an authoritative compendium on the subject.

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