Neuroprosthetics is an area of intense scientific and clinical interest and rapid progress. Since the introduction of the cardiac pacemaker in 1932, we have seen developments that include cochlear prostheses, techniques for bladder and bowel control, deep brain stimulation, and restoration of mobility and respiration to paralyzed individuals. The chapters in this book have been contributed by authors who are recognized internationally in their fields. The result is a comprehensive and up-to-date review that will be invaluable to graduate students, clinicians and researchers in neuroprosthetics. It is broadly divided into three sections: Section 1 provides a core of knowledge that forms a foundation for the rest of the book, and covers the basics of neuroanatomy and neurophysiology, biomaterials and biocompatibility, stimulation and recording techniques; Section 2 describes current clinical applications of neuroprosthetics; Section 3 looks at future developments in the field. Contents:Neuroanatomy and Physiology:Passive Models of Excitable Cells (J J Struijk)Peripheral Nervous System (K W Horch & P R Burgess)Anatomy and Physiology of the Central Nervous System (V K Mushahwar, T Hanania, J Ingram, K E Jones, S K Patrick & K W Horch)Autonomic Nervous System (G S Dhillon & K W Horch)Skeletal Muscle (S Salmons)Voluntary Motor Control (R R Riso)The Visual System as a Neuroprosthesis Substrate: Anatomy, Physiology, Function (G Dagnelie & E Margalit)The Auditory System (R K Shepherd)Neuroplasticity (P A Celnik, M J Makley, E Fridman & L G Cohen)Spinal Plasticity (V Pikov)Extracellular Stimulation and Recording:Electrical Stimulation of the Peripheral Nervous System: Biophysics and Excitation Properties (W M Grill)The Theory of Peripheral Nerve Recording (K Yoshida & J Struijk)Central Nervous System Stimulation (F Rattay)The Theory of Central Nervous System Recording (S Shoham & S Nagarajan)Materials for Stimulation and Recording:Electrode Materials for Recording and Stimulation (T Stieglitz)Insulating Biomaterials (D J Edell)Vapor Deposition of Biopassivation Coatings for Neuroprostheses (S K Murthy, D J Edell & K K Gleason)Tissue Reaction to Electrodes: The Problem of Safe and Effective Stimulation of Neural Tissue (D McCreery)Peripheral Stimulation and Recording:Functional Adaptation of Skeletal Muscle and Its Application to Cardiac Assistance (E Monnet & S Salmons)Peripheral Nerve and Muscle Stimulation (J T Mortimer & N Bhadra)Peripheral Nerve Recording Electrodes and Techniques (K Yoshida & R Riso)Central Stimulation and Recording:Neural Stimulation Electrodes: Geometric Factors (D J Anderson & J Weiland)CNS Recording Electrodes and Techniques (D R Kipke, D S Pellinen & P J Rousche)Spinal Cord and Rootlets (A Prochazka & V K Mushahwar)Existing FES Systems:Control Issues for Motor Neuroprostheses (D B Popovic)Upper and Lower Extremity Motor Neuroprostheses (K L Kilgore & R F Kirsch)Cochlear Implants (P M Seligman & R K Shepherd)Neuromodulation and Other Electrostimulatory Techniques (P E V Van Kerrebroeck)Deep Brain Stimulation (E B Montgomery Jr. & K B Baker)Neural Recording on Close Spaced Arrays (D J Anderson)Respiratory Muscle Stimulation in Patients with Spinal Cord Injury (A F DiMarco)Future FES Systems:The Future of Motor Neuroprostheses (R F Kirsch & K L Kilgore)Challenges to Developing a Neurally Controlled Upper Limb Prosthesis (G S Dhillon & S Meek)Spinal Cord Stimulation for Restoring Lower Extremity Function (V K Mushahwar & A Prochazka)Emerging FES Applications for Control of the Urinary Bladder (N J M Rijkhoff)Can Vision be Restored by Electrical Stimulation? (E Margalit, G Dagnelie, J D Weiland, E de Juan, Jr. & M S Humayun)Central Auditory Prostheses (R K Shepherd)Vestibular Prosthetics (D M Merfeld & R D Rabbitt)Brain-Computer-Interfaces for Verbal Communication (N Birbaumer, U Strehl & T Hinterberger)Design Principles of a Neuromotor Prosthetic Device (M Serruya & J Donoghue)Next Generation of Cortical Devices (P J Rousche & D R Kipke)Regulatory Issues:Biocompatibility of Neuroprotheses (Jeffery R Nelson & Jerry R Nelson) Readership: Graduate students, academics, researchers and clinicians in biomedical engineering/bioengineering, neurobiology, neurology/neuroscience and human physiology. Keywords:
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